The Cat Lady

This game gets pretty rough, so we should start with some content warnings for suicide, mental illness, depression, and murder.

The Cat Lady is an independent horror adventure game that stars Susan Ashworth, a woman suffering from trauma and depression, who is pressed into the service of an eldritch being, and tasked with eliminating "Parasites"... indiscriminate killers who surround her. Susan's only hope in this dismal affair is an unexpected new friend with problems of her own. The Cat Lady isn't perfect, but it's extremely strongly stated in a way that is rare for games of any scope.